Prentice Award Lecture 2010:
A Case for Peripheral Optical Treatment Strategies for Myopia

CONCLUSIONS: The overall pattern of results suggests that optical treatment strategies for myopia that take into account the effects of peripheral vision are likely to be more successful than strategies that effectively manipulate only central vision. {Read More…}

The SMART Study:
Background, Rationale,and Baseline Results

CONCLUSIONS: It is evident that interest in overnight ortho-k for young people is growing based upon the numerous clinical studies performed in recent years. However, these studies have only evaluated subjects over a period of no more than two years and often for only six months or less. In addition, the need for a large multicenter longitudinal study that evaluates eye growth, effects of regression over time, ocular health, and corneal thickness change is ery evident. {Read More…}

Retardation of Myopia in Orthokeratology (ROMIO) Study:
A 2-Year Randomized Clinical Trial

CONCLUSIONS: On average, subjects wearing ortho-k lenses had a slower increase in axial elongation by 43% compared with that of subjects wearing single-vision glasses. Younger children tended to have faster axial elongation and may benefit from early ortho-k treatment. {Read More…}

Outdoor Activity Reduces the Prevalence of Myopia in Children

CONCLUSIONS: Higher levels of total time spent outdoors, rather than sport per se, were associated with less myopia and a more hyperopic mean refraction, after adjusting for near work, parental myopia, and ethnicity. {Read More…}

Myopia Control with Orthokeratology Contact Lenses in Spain (MCOS):
Study Design and General Baseline Characteristics

CONCLUSIONS: To the authors’ knowledge, MCOS is the first prospective clinical trial to assess the safety and efficacy of orthokeratology contact lens wear to slow myopia progression vs. single-vision spectacle wear. The MCOS offers a number of notable features: prospective design; well-matched samples and high-resolution ocular biometry measures, which should collectively elucidate whether orthokeratology contact lens wear is a feasible and safe method for myopia-progression control.{Read More…}

The Longitudinal Orthokeratology Research in Children (LORIC) in Hong Kong: A Pilot Study on Refractive Changes and Myopic Control

CONCLUSIONS: Ortho-k can have both a corrective and preventive/control effect in childhood myopia. However, there are substantial variations in changes in eye length among children and there is no way to predict the effect for individual subjects. {Read More…}

The Children's Overnight Orthokeratology Investigation (COOKI) Pilot Study

CONCLUSIONS: Overnight cornea-reshaping contact lenses are efficacious for young myopic patients, and no children experienced a serious adverse event during the study. {Read More…}